Vitamin D: a ‘wanted’ supernatural power or a power of wishful thinking

The current issue of CEJU brings a somewhat ambiguous paper entitled “Vitamin D and urological cancers” describing (possible) role of the vit. D in the etiology of urological cancers [1]. Indeed, last years brought numerous publications presenting that 1,25-dihydroxyvitamin D3 may alter human susceptibility to different diseases (even improve fitness) and its capability to cure or, at least, to soothe some human cancers [2, 3, 4]. Such contribution of the vit. D has been debated widely elsewhere, became trendy in contemporary medicine and engaged a great number of researches. Vit D and polymorphism of its targeted receptors have been harnessed to the etiology of: hypertension, bronchial asthma, type 2 diabetes mellitus, autoimmune disorders, cognitive decline and so forth [5]. Some studies suggest that vit. D receptor polymorphism may play a role in the prostate cancer, bladder cancer and other malicious tumours [6, 7]. Its role in the progress of the colon cancer has been scientifically proven [6]. The evidence for a protective effect of vitamin D on the risk of breast cancer has been published before. Thus, it looked that medicine found a gorgeous but simple and attainable remedy for almost everything. Paper under discussion keeps pace with that papers and I am convinced that is worthy of notice as a well-tailored analysis adding a new twist to that issue [1]. Although considerable progress has been made toward understanding tumours etiology and the role of vit. D in human pathology, its role in cancer is still unclear [8, 9], Some papers present conflicting data clearly demonstrated in the manuscript under debate. Authors performed a survey of eligible studies Vitamin D: a ‘wanted’ supernatural power or a power of wishful thinking